個人簡歷

　　主任醫(yī)師，教授，神經(jīng)疾病高創(chuàng)中心科主任

　　專業(yè)特長：

　　賈建平是一位臨床經(jīng)驗豐富和科學(xué)理論精到的臨床科學(xué)家，中央保健醫(yī)生，2018年被評為國之名醫(yī)，從事神經(jīng)科臨床工作30余年，長期的臨床實踐造就了精湛的醫(yī)療技術(shù)，一直在臨床第一線工作，經(jīng)治了來自全國各地疑難病患者，參加數(shù)以萬計的國內(nèi)外會診，對常見病、多發(fā)病、疑難雜癥的診治有獨(dú)到的臨床思維和絕技，倡導(dǎo)“每個疾病千差萬別，要帶著研究的態(tài)度來看病”，這一觀點曾被中央電視臺《東方之子》欄目組作過全面報道，被同行和社會民眾公認(rèn)為神經(jīng)科代表性人物。

　　科研與教學(xué)水平：

　　先后主持并參與了國家自然科學(xué)基金委員會重點重大項目五項，973等科技部項目十余項，其他省部級項目十余項,發(fā)表相關(guān)論文960余篇，其中SCI 257篇，在Lancet Neurology，Lancet Public Health，Alzheimer & Dementia，Nature Communications，Brain等著名學(xué)術(shù)期刊發(fā)表IF≥10分27篇，總被引16000余次。連續(xù)主編全國高等醫(yī)學(xué)院校《神經(jīng)病學(xué)》教材第6、7、8版及其他教材、著作共56部，被稱為我國神經(jīng)病學(xué)教材主編第一人。

　　個人榮譽(yù)：

　　擔(dān)任中華醫(yī)學(xué)會神經(jīng)病學(xué)分會主任委員(2007年候任主委，2010年任主委，2013年任前任主委，2016年任名譽(yù)主委)、中國醫(yī)師協(xié)會神經(jīng)內(nèi)科分會會長(2004年會長，2009年連任會長，2017年-至今任前任會長)、北京醫(yī)學(xué)會神經(jīng)病學(xué)分會主任委員、中華醫(yī)學(xué)會神經(jīng)病學(xué)分會癡呆與認(rèn)知障礙學(xué)組組長、中國醫(yī)師協(xié)會神經(jīng)內(nèi)科醫(yī)師分會認(rèn)知障礙疾病專業(yè)委員會主任委員。擔(dān)任首都醫(yī)科大學(xué)神經(jīng)病學(xué)系主任、首都醫(yī)科大學(xué)神經(jīng)變性病與記憶障礙疾病臨床診療與研究中心主任、首都醫(yī)科大學(xué)神經(jīng)病學(xué)研究所所長、北京腦重大疾病研究院阿爾茨海默病研究所所長、老年認(rèn)知障礙疾病北京重點實驗室主任。以及《Alzheimer’s & Dementia》、《Alzheimer’s Research & Therapy》、《Current Alzheimer Research》、《Journal of Alzheimer’s Disease》、《中華神經(jīng)科雜志》、《中華醫(yī)學(xué)雜志》等20種學(xué)術(shù)刊物的主編、副主編及編委等多項學(xué)術(shù)團(tuán)體職務(wù)。先后獲得國家科學(xué)技術(shù)進(jìn)步獎二等獎、國之名醫(yī)、藥明康德生命化學(xué)研究獎、中國杰出神經(jīng)內(nèi)科醫(yī)師學(xué)術(shù)成就獎、北京市十百千人才十層次人才、北京市衛(wèi)生系統(tǒng)高層次領(lǐng)軍人才、國務(wù)院政府特殊津貼專家、中國醫(yī)師獎等二十余項榮譽(yù)。

　　代表性論著：

　　1. Jia L, Zhu M, Kong C, Pang Y, Zhang H, Qiu Q, Wei C, Tang Y, Wang Q, Li Y, Li T, Li F, Wang Q, Li Y, Wei Y, Jia J*. Blood neuro-exosomal synaptic proteins predict Alzheimer’s disease at the asymptomatic stage. Alzheimers Dement. Dement.2021; 17(1):49-60

　　2. Jia L, Quan M, Fu Y, Zhao T, Li Y, Wei C, Tang Y, Qin Q, Wang F, Qiao Y, Shi S, Wang YJ, Du Y, Zhang J, Zhang J, Luo B, Qu Q, Zhou C, Gauthier S, Jia J*, Group for the Project of Dementia Situation in C. Dementia in China: epidemiology, clinical management, and research advances. Lancet Neurol. 2020; 19:81-92.

　　3. Jia L, Fu Y, Shen L, Zhang H, Zhu M, Qiu Q, Wang Q, Yan X, Kong C, Hao J, Wei C, Tang Y, Qin W, Li Y, Wang F, Guo D, Zhou A, Zuo X, Yu Y, Li D, Zhao L, Jin H, Jia J*. PSEN1, PSEN2, and APP mutations in 404 Chinese pedigrees with familial Alzheimer's disease. Alzheimers Dement. 2020;16(1):178-91.

　　4. Jia L, Xu H, Chen S, Wang X, Yang J, Gong M, Wei C, Tang Y, Qu Q, Chu L, Shen L, Zhou C, Wang Q, Zhao T, Zhou A, Li Y, Li F, Li Y, Jin H, Qin Q, Jiao H, Li Y, Zhang H, Lyu D, Shi Y, Song Y, Jia J*. The APOE-ε4 exerts differential effects on familial and other subtypes of Alzheimer’s disease. Alzheimers Dement. 2020. DOI: 10.1002/alz.12153.

　　5. Jia L, Du Y, Chu L, Zhang Z, Li F, Lyu D, Li Y, Li Y, Zhu M, Jiao H, Song Y, Shi Y, Zhang H, Gong M, Wei C, Tang Y, Fang B, Guo D, Wang F, Zhou A, Chu C, Zuo X, Yu Y, Yuan Q, Wang W, Li F, Shi S, Yang H, Zhou C, Liao Z, Lv Y, Li Y, Kan M, Zhao H, Wang S, Yang S, Li H, Liu Z, Wang Q, Qin W, Jia J; COAST Group. Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study. Lancet Public Health. 2020;5(12):e661-e671.

　　6. Jia L, Li F, Wei C, Zhu M, Qu Q, Qin W, Tang Y, Shen L, Wang Y, Shen L, Li H, Peng D, Tan L, Luo B, Guo Q, Tang M, Du Y, Zhang J, Zhang J, Lyu J, Li Y, Zhou A, Wang F, Chu C, Song H, Wu L, Zuo X, Han Y, Liang J, Wang Q, Jin H, Wang W, Lü Y, Li F, Zhou Y, Zhang W, Liao Z, Qiu Q, Li Y, Kong C, Li Y, Jiao H, Lu J, Jia J*. Prediction of Alzheimer's disease using multi-variants from a Chinese genome-wide association study. Brain. 2020. DOI: 10.1093/brain/awaa364

　　7. Jia L, Qiu Q, Zhang H, Chu L, Du Y, Zhang J, Zhou C, Liang F, Shi S, Wang S, Qin W, Wang Q, Li F, Wang Q, Li Y, Shen L, Wei Y, Jia J*. Concordance between the assessment of Abeta42, T-tau, and P-T181-tau in peripheral blood neuronal-derived exosomes and cerebrospinal fluid. Alzheimers Dement. 2019;15(8):1071-80.

　　8. Tang Y, Xing Y, Zhu Z, He Y, Li F, Yang J, Liu Q, Li F, Teipel S, Zhao G, Jia J*. The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial. Alzheimers Dement. 2019;15(5):605-14.

　　9. Wang Z, Gong K, Liu X, Zhang Z, Sun X, Wei Z, Yu S, Manfredsson FP, Sandoval IM, Johnson PF, Jia J*, Wang J, Ye K. C/EBPbeta regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease. Nat Commun. 2018;9(1):1784.

　　10. Jia J*, Wei C, Chen S, Li F, Tang Y, Qin W, Zhao L, Jin H, Xu H, Wang F, Zhou A, Zuo X, Wu L, Han Y, Han Y, Huang L, Wang Q, Li D, Chu C, Shi L, Gong M, Du Y, Zhang J, Zhang J, Zhou C, Lv J, Lv Y, Xie H, Ji Y, Li F, Yu E, Luo B, Wang Y, Yang S, Qu Q, Guo Q, Liang F, Zhang J, Tan L, Shen L, Zhang K, Zhang J, Peng D, Tang M, Lv P, Fang B, Chu L, Jia L, Gauthier S. The cost of Alzheimer's disease in China and re-estimation of costs worldwide. Alzheimers Dement. 2018;14(4):483-91.

　　11. Jia J*, Gauthier S, Pallotta S, Ji Y, Wei W, Xiao S, Peng D, Guo Q, Wu L, Chen S, Kuang W, Zhang J, Wei C, Tang Y. Consensus-based recommendations for the management of rapid cognitive decline due to Alzheimer's disease. Alzheimers Dement. 2017:592-7.

　　12. Jia J*, Zuo X, Jia XF, Chu C, Wu L, Zhou A, Wei C, Tang Y, Li D, Qin W, Song H, Ma Q, Li J, Sun Y, Min B, Xue S, Xu E, Yuan Q, Wang M, Huang X, Fan C, Liu J, Ren Y, Jia Q, Wang Q, Jiao L, Xing Y, Wu X, China C, Aging Study G. Diagnosis and treatment of dementia in neurology outpatient departments of general hospitals in China. Alzheimers Dement. 2016;12(4):446-53.

　　13. Jia J*, Wei C, Liang J, Zhou A, Zuo X, Song H, Wu L, Chen X, Chen S, Zhang J, Wu J, Wang K, Chu L, Peng D, Lv P, Guo H, Niu X, Chen Y, Dong W, Han X, Fang B, Peng M, Li D, Jia Q, Huang L. The effects of DL-3-n-butylphthalide in patients with vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease: A multicentre, randomized, double-blind, placebo-controlled trial. Alzheimers Dement. 2016;12(2):89-99.

　　14. Zhang Z, Song M, Liu X, Su Kang S, Duong DM, Seyfried NT, Cao X, Cheng L, Sun YE, Ping Yu S, Jia J*, Levey AI, Ye K. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nat Commun. 2015;6:8762.

　　15. Tang Y, Wang X, Jia J*. Mercury poisoning presenting as sporadic Creutzfeldt-Jakob disease: a case report. Ann Intern Med. 2015;162(6):462-3.

　　16. Jia J*, Zhou A, Wei C, Jia X, Wang F, Li F, Wu X, Mok V, Gauthier S, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement. 2014;10(4):439-47.

　　17. Jia J*, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement. 2014;10(1):1-9.

　　18. Xing Y, Jia J*, Ji, X, Tian, T. Estrogen associated gene polymorphisms and their interactions in the progress of Alzheimer's disease. Prog Neurobiol. 2013;111:53-74.

　　19. Jia J, Pollock M, Jia JM. Cold injury to nerves is not due to ischaemia alone. Brain. 1998;121: 989-1001.

　　20. Jia J, Pollock M. The pathogenesis of non-freezing cold nerve injury. Observations in the rat. Brain. 1997;120: 631-46.

　　21. 中華醫(yī)學(xué)會神經(jīng)病學(xué)分會癡呆與認(rèn)知障礙學(xué)組寫作組，賈建平*. 血管性認(rèn)知障礙診治指南. 中華神經(jīng)科雜志. 2011, 44(2): 141-147.

　　22. 賈建平主編. 中國癡呆與認(rèn)知障礙診治指南：人民衛(wèi)生出版社，2010，北京.

　　23. 賈建平主編. 中國癡呆與認(rèn)知障礙診治指南(2015年版)：人民衛(wèi)生出版社，2016，北京.

　　24. 賈建平，陳生弟主編. 神經(jīng)病學(xué)(第8版)：人民衛(wèi)生出版社，2018，北京.

　　25. 賈建平，陳生弟主編. 神經(jīng)病學(xué)(第7版)：人民衛(wèi)生出版社，2013，北京.

　　26. 賈建平主編. 神經(jīng)病學(xué)(第6版)：人民衛(wèi)生出版社，2008，北京.